Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
HD6
JM21 KIAA0901 |
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases |
| gptkbp:biologicalProcess |
histone deacetylase activity
tubulin deacetylase activity |
| gptkbp:domain |
two catalytic deacetylase domains
zinc finger ubiquitin-binding domain |
| gptkbp:EC_number |
3.5.1.98
|
| gptkbp:encodedBy |
gptkb:HDAC6_gene
|
| gptkbp:function |
deacetylation of lysine residues on histone and non-histone proteins
|
| gptkbp:gene |
gptkb:HDAC6
|
| https://www.w3.org/2000/01/rdf-schema#label |
Histone deacetylase 6
|
| gptkbp:involves |
protein degradation
cell motility stress response aggresome formation |
| gptkbp:locatedOnChromosome |
Xq11.2-q23
|
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:proteinFamily |
histone deacetylase family
|
| gptkbp:target |
HDAC inhibitors
|
| gptkbp:UniProtID |
gptkb:Q9UBN7
|
| gptkbp:bfsParent |
gptkb:HDAC6
|
| gptkbp:bfsLayer |
7
|