High-density lipoprotein (HDL)
GPTKB entity
Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
lipoprotein
|
| gptkbp:abbreviation |
HDL
|
| gptkbp:affects |
gptkb:food
genetics alcohol consumption smoking exercise |
| gptkbp:alsoKnownAs |
good cholesterol
|
| gptkbp:associatedWith |
reduced risk of cardiovascular disease
|
| gptkbp:category |
lipoprotein
biomarker cholesterol carrier |
| gptkbp:component |
gptkb:apolipoprotein_A-I
cholesterol blood plasma phospholipids triglycerides |
| gptkbp:contrastsWith |
gptkb:low-density_lipoprotein_(LDL)
very-low-density lipoprotein (VLDL) |
| gptkbp:discoveredBy |
gptkb:John_Gofman
|
| gptkbp:discoveredIn |
1950
|
| gptkbp:function |
transports cholesterol from tissues to liver
removes excess cholesterol from bloodstream |
| gptkbp:highLevelEffect |
protective against atherosclerosis
|
| https://www.w3.org/2000/01/rdf-schema#label |
High-density lipoprotein (HDL)
|
| gptkbp:lowLevelRisk |
increased risk of heart disease
|
| gptkbp:measures |
gptkb:HDL_cholesterol_test
|
| gptkbp:range |
men: 40–60 mg/dL
women: 50–60 mg/dL |
| gptkbp:relatedTo |
gptkb:apolipoprotein_E
gptkb:fibrates gptkb:apolipoprotein_C gptkb:metabolic_syndrome niacin atherosclerosis coronary artery disease statins triglycerides apolipoprotein A-II total cholesterol cholesteryl ester transfer protein (CETP) lecithin–cholesterol acyltransferase (LCAT) scavenger receptor class B type 1 (SR-B1) |
| gptkbp:role |
reverse cholesterol transport
|
| gptkbp:subspecies |
gptkb:HDL2
gptkb:HDL3 |
| gptkbp:synthesisType |
liver
intestine |
| gptkbp:bfsParent |
gptkb:Cholesterol
|
| gptkbp:bfsLayer |
6
|