|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:ApoA-I
|
|
gptkbp:associatedWith
|
gptkb:Tangier_disease
gptkb:familial_HDL_deficiency
|
|
gptkbp:component
|
high-density lipoprotein
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000118137
|
|
gptkbp:expressedIn
|
gptkb:small_intestine
liver
|
|
gptkbp:foundIn
|
gptkb:human
other mammals
|
|
gptkbp:function
|
cholesterol transport
activates lecithin-cholesterol acyltransferase
|
|
gptkbp:gene
|
gptkb:APOA1
|
|
gptkbp:interactsWith
|
ABCA1 transporter
LCAT enzyme
|
|
gptkbp:length
|
243 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 11q23-q24
|
|
gptkbp:molecularWeight
|
28 kDa
|
|
gptkbp:mutationAssociatedWith
|
can cause hypoalphalipoproteinemia
|
|
gptkbp:OMIM
|
107680
|
|
gptkbp:PDB
|
2A01
|
|
gptkbp:postTranslationalModification
|
oxidation
glycation
|
|
gptkbp:RefSeq
|
NP_000030.1
|
|
gptkbp:role
|
reverse cholesterol transport
|
|
gptkbp:significance
|
biomarker for cardiovascular disease
|
|
gptkbp:structure
|
amphipathic alpha-helix
|
|
gptkbp:subunit
|
gptkb:HDL_particle
|
|
gptkbp:UniProtID
|
P02647
|
|
gptkbp:bfsParent
|
gptkb:APOA1
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
apolipoprotein A-I
|