High-affinity immunoglobulin epsilon receptor
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:FcεRI
|
| gptkbp:binds |
gptkb:IgE
|
| gptkbp:component |
alpha chain
beta chain gamma chain |
| gptkbp:discoveredBy |
1970s
|
| gptkbp:expressedIn |
gptkb:basophils
gptkb:mast_cells |
| gptkbp:function |
mediates allergic response
triggers degranulation |
| gptkbp:gene |
gptkb:FCER1A
gptkb:FCER1B gptkb:FCER1G |
| https://www.w3.org/2000/01/rdf-schema#label |
High-affinity immunoglobulin epsilon receptor
|
| gptkbp:involvedIn |
anaphylaxis
type I hypersensitivity allergic asthma |
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:OMIM |
147139 (alpha chain)
|
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:structure |
tetrameric (αβγ2) or trimeric (αγ2)
|
| gptkbp:UniProtID |
P12319 (alpha chain)
|
| gptkbp:bfsParent |
gptkb:FcεRI
|
| gptkbp:bfsLayer |
8
|