Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
allergic inflammation
histamine release degranulation |
| gptkbp:component |
alpha chain
beta chain gamma chain |
| gptkbp:discoveredIn |
1970s
|
| gptkbp:expressedIn |
gptkb:basophils
gptkb:mast_cells gptkb:eosinophils antigen-presenting cells |
| gptkbp:fullName |
gptkb:High-affinity_immunoglobulin_epsilon_receptor
|
| gptkbp:function |
mediates allergic responses
binds IgE antibodies |
| gptkbp:gene |
gptkb:FCER1A
gptkb:FCER1B gptkb:FCER1G |
| https://www.w3.org/2000/01/rdf-schema#label |
FcεRI
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:relatedTo |
asthma
anaphylaxis allergic diseases |
| gptkbp:structure |
tetrameric in humans (αβγ2)
trimeric in rodents (αγ2) |
| gptkbp:target |
anti-IgE therapy
|
| gptkbp:UniProtID |
P12319 (alpha chain)
|
| gptkbp:bfsParent |
gptkb:FcεR
gptkb:mast_cells |
| gptkbp:bfsLayer |
7
|