Hepatitis B virus

GPTKB entity

Statements (63)
Predicate Object
gptkbp:instance_of gptkb:virus
gptkbp:associated_with chronic liver disease
extrahepatic manifestations
increased liver cancer risk
gptkbp:cause Hepatitis B infection
gptkbp:community_health in many countries
gptkbp:condition gptkb:hepatocellular_carcinoma
liver failure
hepatitis D virus co-infection
gptkbp:data_usage higher in healthcare settings
gptkbp:diagnosis blood test
gptkbp:discovered_by gptkb:1967
gptkbp:diseases can lead to liver cancer
can lead to liver cirrhosis
may be asymptomatic
can resolve spontaneously
gptkbp:duration may last for years
gptkbp:epidemiology endemic in Asia and Africa
gptkbp:family gptkb:Hepadnaviridae
https://www.w3.org/2000/01/rdf-schema#label Hepatitis B virus
gptkbp:incubation_period 30 to 180 days
gptkbp:is_vulnerable_to gptkb:HBV_vaccine
gptkbp:liver_biopsy used for assessing liver damage
gptkbp:liver_transplant may be necessary in severe cases
gptkbp:prevalence approximately 257 million people infected
gptkbp:prevention vaccination
safe sex practices
avoid sharing needles
gptkbp:recommendation universal vaccination of infants
gptkbp:research_focus immune response
vaccine development
pathogenesis
antiviral resistance
gptkbp:risk_factor travel to endemic areas
multiple sexual partners
unprotected sex
healthcare exposure
injection drug use
gptkbp:risk_of_transmission higher in chronic carriers
gptkbp:seed_dispersal partially double-stranded DNA
gptkbp:serological_marker HBs Ag
anti-HBc
anti-HBs
gptkbp:symptoms fatigue
nausea
abdominal pain
jaundice
loss of appetite
gptkbp:transmission gptkb:blood
sexual contact
mother to child
gptkbp:treatment antiviral medications
interferon therapy
suppress viral replication
prevent liver damage
nucleos(t)ide analogs
reduce risk of liver cancer
gptkbp:type_of adr
adw
ayw
gptkbp:bfsParent gptkb:Hepadnaviridae
gptkb:Hepatitis_B
gptkbp:bfsLayer 6