Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
hemoglobin
|
| gptkbp:affects |
oxygen transport
|
| gptkbp:alsoKnownAs |
gptkb:HbS
|
| gptkbp:aminoAcidChange |
glutamic acid to valine at position 6
|
| gptkbp:cause |
gptkb:anemia
sickle cell disease organ damage vaso-occlusive crises |
| gptkbp:detects |
genetic testing
hemoglobin electrophoresis |
| gptkbp:discoveredBy |
gptkb:James_V._Neel
|
| gptkbp:discoveredIn |
1949
|
| gptkbp:form |
sickle-shaped red blood cells under low oxygen
|
| gptkbp:foundIn |
red blood cells
|
| https://www.w3.org/2000/01/rdf-schema#label |
Hemoglobin S
|
| gptkbp:inheritance |
autosomal recessive
|
| gptkbp:mutationAssociatedWith |
gptkb:HBB_gene
|
| gptkbp:prevalence |
gptkb:Mediterranean_populations
gptkb:Middle_Eastern_populations African descent Indian populations |
| gptkbp:resistantTo |
malaria
|
| gptkbp:treatment |
gptkb:hydroxyurea
blood transfusion bone marrow transplant |
| gptkbp:bfsParent |
gptkb:HbS
|
| gptkbp:bfsLayer |
7
|