Statements (31)
Predicate | Object |
---|---|
gptkbp:instanceOf |
Abnormal red blood cell
|
gptkbp:associatedWith |
gptkb:Sickle_cell_disease
|
gptkbp:cause |
gptkb:Splenic_sequestration
gptkb:Vaso-occlusion Stroke Increased risk of infection Hemolytic anemia Organ damage Painful crises |
gptkbp:causedBy |
Mutation in HBB gene
|
gptkbp:contains |
gptkb:Hemoglobin_S
|
gptkbp:diagnosedBy |
gptkb:Hemoglobin_electrophoresis
Blood smear |
gptkbp:discoveredBy |
gptkb:James_B._Herrick
|
gptkbp:firstDescribed |
1910
|
gptkbp:foundIn |
gptkb:Humans
|
https://www.w3.org/2000/01/rdf-schema#label |
Sickle Cells
|
gptkbp:inheritance |
Autosomal recessive
|
gptkbp:lifespan |
10-20 days
|
gptkbp:normalCellLifespan |
120 days
|
gptkbp:prevalence |
gptkb:India
gptkb:Middle_East gptkb:Sub-Saharan_Africa gptkb:Mediterranean_region |
gptkbp:protectedBy |
gptkb:Malaria
|
gptkbp:shape |
gptkb:Crescent
|
gptkbp:treatment |
gptkb:Bone_marrow_transplant
gptkb:Hydroxyurea Blood transfusion |
gptkbp:bfsParent |
gptkb:Red_Blood_Morphology
|
gptkbp:bfsLayer |
7
|