Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:HSPA1A
Heat shock protein 72 |
| gptkbp:encodedBy |
gptkb:HSPA1A_gene
|
| gptkbp:expressedIn |
many tissues
|
| gptkbp:function |
protein folding
molecular chaperone protection against cellular stress |
| https://www.w3.org/2000/01/rdf-schema#label |
HSP72
|
| gptkbp:inducedBy |
heat shock
cellular stress |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
chromosome 6p21.3
|
| gptkbp:memberOf |
gptkb:HSP70_family
|
| gptkbp:molecularWeight |
72 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:role |
prevention of protein aggregation
protein homeostasis cellular protection during stress |
| gptkbp:significance |
implicated in cancer
implicated in neurodegenerative diseases biomarker for cellular stress |
| gptkbp:structure |
contains ATPase domain
contains substrate-binding domain |
| gptkbp:UniProtID |
gptkb:P0DMV8
|
| gptkbp:bfsParent |
gptkb:Heat_shock_70_kDa_protein_1A
gptkb:hsa:3043 gptkb:HSPA1A gptkb:HSPA1A_(human) |
| gptkbp:bfsLayer |
8
|