Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alternativeName |
gptkb:GAD2
gptkb:GAD65 |
gptkbp:associatedWith |
type 1 diabetes
|
gptkbp:autoantigenIn |
type 1 diabetes
|
gptkbp:catalyzes |
decarboxylation of glutamate to GABA
|
gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
gptkbp:EC_number |
4.1.1.15
|
gptkbp:encodedBy |
gptkb:GAD2_gene
|
gptkbp:expressedIn |
gptkb:pancreatic_islets
neurons |
gptkbp:foundIn |
gptkb:human
brain |
https://www.w3.org/2000/01/rdf-schema#label |
Glutamate decarboxylase 65
|
gptkbp:inhibitedBy |
antibodies in autoimmune diabetes
|
gptkbp:locatedOnChromosome |
chromosome 10q23.33
|
gptkbp:molecularWeight |
65 kDa
|
gptkbp:OMIM |
138275
|
gptkbp:subcellularLocation |
cytosol
synaptic vesicles |
gptkbp:UniProtID |
Q05329
|
gptkbp:bfsParent |
gptkb:GAD65
|
gptkbp:bfsLayer |
7
|