Gastrointestinal stromal tumor

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:disease
gptkbp:abbreviation	gptkb:GIST
gptkbp:affects	adults children gastrointestinal tract
gptkbp:annualIncidence	10-20 per million
gptkbp:diagnosedBy	immunohistochemistry
gptkbp:firstDescribed	1983
gptkbp:frequency	rare
gptkbp:hasMetastasisSite	liver peritoneum rarely lymph nodes
gptkbp:ICD-10_code	C49.A
gptkbp:location	stomach
gptkbp:malignantPotential	variable
gptkbp:marking	gptkb:CD117 gptkb:DOG1
gptkbp:MeSH_ID	D018223
gptkbp:mutationAssociatedWith	gptkb:KIT_gene gptkb:PDGFRA_gene
gptkbp:notResponsiveTo	gptkb:radiation_therapy conventional chemotherapy
gptkbp:occurredIn	colon esophagus rectum
gptkbp:OMIM	606764
gptkbp:origin	gptkb:interstitial_cells_of_Cajal
gptkbp:prognosis	depends on size and mitotic rate
gptkbp:relatedTo	gptkb:rhabdomyosarcoma
gptkbp:riskFactor	gptkb:neurofibromatosis_type_1 Carney's triad
gptkbp:secondMostCommonLocation	gptkb:small_intestine
gptkbp:subspecies	SDH-deficient GIST pediatric GIST wild-type GIST
gptkbp:symptom	nausea vomiting abdominal pain gastrointestinal bleeding weight loss
gptkbp:treatment	gptkb:imatinib gptkb:regorafenib gptkb:sunitinib surgery
gptkbp:UMLS_CUI	C0206686
gptkbp:bfsParent	gptkb:GIST gptkb:Small_intestine_cancer
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	Gastrointestinal stromal tumor