GRK6

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alias GPRK6
GPRK6A
GRK6A
gptkbp:alternativeSplicing yes
gptkbp:associatedWith gptkb:Parkinson's_disease
immune response
gptkbp:biologicalProcess protein kinase activity
gptkbp:cellularComponent gptkb:cytoplasm
gptkb:plasma_membrane
gptkbp:discoveredBy researchers in the 1990s
gptkbp:encodes G protein-coupled receptor kinase 6 protein
gptkbp:Entrez_Gene_ID 2870
gptkbp:expressedIn various tissues including brain, heart, and leukocytes
gptkbp:fullName G protein-coupled receptor kinase 6
gptkbp:function phosphorylates activated G protein-coupled receptors
gptkbp:geneType protein-coding
gptkbp:HGNC_ID HGNC:4556
https://www.w3.org/2000/01/rdf-schema#label GRK6
gptkbp:involvedIn desensitization of GPCRs
regulation of GPCR signaling
gptkbp:locatedOnChromosome gptkb:chromosome_5
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse Grk6
gptkbp:proteinFamily serine/threonine protein kinase
gptkbp:UniProtID P43250
gptkbp:bfsParent gptkb:G_protein-coupled_receptor_kinase
gptkbp:bfsLayer 8