Statements (30)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alternativeName |
GPRK4
GRK4 alpha GRK4 beta GRK4 delta GRK4 gamma |
gptkbp:associatedWith |
hypertension
|
gptkbp:discoveredBy |
Benovic et al.
|
gptkbp:encodes |
G protein-coupled receptor kinase 4 protein
|
gptkbp:Entrez_Gene_ID |
2868
ENSG00000185022 |
gptkbp:expressedIn |
gptkb:kidney
gptkb:testis brain |
gptkbp:fullName |
G protein-coupled receptor kinase 4
|
gptkbp:function |
phosphorylates activated G protein-coupled receptors
|
gptkbp:HGNC_ID |
4555
|
https://www.w3.org/2000/01/rdf-schema#label |
GRK4
|
gptkbp:locatedOnChromosome |
gptkb:4p16.3
|
gptkbp:mutationAssociatedWith |
essential hypertension
|
gptkbp:OMIM |
601434
|
gptkbp:organism |
gptkb:Homo_sapiens
|
gptkbp:orthologInMouse |
Grk4
|
gptkbp:proteinFamily |
serine/threonine protein kinase
|
gptkbp:RefSeq |
NM_001482
|
gptkbp:regulates |
gptkb:dopamine_receptor_D1
gptkb:dopamine_receptor_D3 |
gptkbp:UniProtID |
P32298
|
gptkbp:bfsParent |
gptkb:G_protein-coupled_receptor_kinase
|
gptkbp:bfsLayer |
8
|