Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
GLI3 zinc finger protein
GLI-Kruppel family member 3 |
| gptkbp:associatedWith |
gptkb:GLI1_gene
gptkb:GLI2_gene polydactyly Greig cephalopolysyndactyly syndrome Pallister-Hall syndrome |
| gptkbp:discoveredBy |
researchers studying limb development
|
| gptkbp:encodes |
GLI3 protein
|
| gptkbp:Entrez_Gene_ID |
2737
|
| gptkbp:expressedIn |
central nervous system
embryonic tissues limb bud |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
transcription factor
regulation of gene expression |
| gptkbp:HGNC_ID |
HGNC:4311
|
| https://www.w3.org/2000/01/rdf-schema#label |
GLI3 gene
|
| gptkbp:locatedOnChromosome |
chromosome 7p14.1
|
| gptkbp:mutationAssociatedWith |
developmental abnormalities
|
| gptkbp:OMIM |
165240
|
| gptkbp:orthologInMouse |
Gli3
|
| gptkbp:pathway |
gptkb:Hedgehog_signaling_pathway
|
| gptkbp:proteinFamily |
zinc finger domain
activator domain repressor domain |
| gptkbp:regulates |
cell differentiation
pattern formation acts as both activator and repressor |
| gptkbp:UniProtID |
P10071
|
| gptkbp:bfsParent |
gptkb:GLI
|
| gptkbp:bfsLayer |
7
|