|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
GDNF family receptor alpha-like protein
GDNF receptor alpha-like
|
|
gptkbp:associatedWith
|
appetite suppression
body weight regulation
|
|
gptkbp:cellularComponent
|
gptkb:cell_membrane
|
|
gptkbp:discoveredBy
|
2017
|
|
gptkbp:encodedBy
|
GFRAL gene
|
|
gptkbp:Entrez_Gene_ID
|
ENSG00000186105
144165
|
|
gptkbp:expressedIn
|
gptkb:nucleus_of_the_solitary_tract
area postrema
|
|
gptkbp:fullName
|
GDNF family receptor alpha-like
|
|
gptkbp:function
|
mediates anorectic effects of GDF15
receptor for GDF15
|
|
gptkbp:HGNC_ID
|
HGNC:25527
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
GFRAL
|
|
gptkbp:ligand
|
gptkb:GDF15
|
|
gptkbp:locatedOnChromosome
|
gptkb:6q22.1
|
|
gptkbp:OMIM
|
618255
|
|
gptkbp:orthologIn
|
gptkb:mouse
right
|
|
gptkbp:pathway
|
GDF15 signaling pathway
|
|
gptkbp:proteinFamily
|
GDNF receptor family
|
|
gptkbp:relatedTo
|
nausea
cachexia
energy homeostasis
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:target
|
therapeutic research for anorexia
therapeutic research for obesity
|
|
gptkbp:UniProtID
|
Q6UXV0
|
|
gptkbp:bfsParent
|
gptkb:GDF15
|
|
gptkbp:bfsLayer
|
7
|