Statements (47)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:SE_gene
gptkb:Secretor_gene gptkb:FUT2_gene H blood group precursor fucosyltransferase Secretor type alpha(1,2)fucosyltransferase alpha(1,2)fucosyltransferase 2 galactoside 2-alpha-L-fucosyltransferase 2 |
| gptkbp:associated_with_phenotype |
secretor status
non-secretor status |
| gptkbp:biologicalProcess |
immune response
protein glycosylation cell-cell recognition fucosyltransferase activity |
| gptkbp:encodes |
gptkb:alpha(1,2)fucosyltransferase
|
| gptkbp:Entrez_Gene_ID |
2524
|
| gptkbp:enzymeCommissionNumber |
2.4.1.69
|
| gptkbp:expressedIn |
gastrointestinal tract
salivary glands epithelial cells respiratory tract |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
determines secretor status in humans
catalyzes the transfer of fucose to oligosaccharides |
| gptkbp:gene |
gptkb:FUT2
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
4017
|
| https://www.w3.org/2000/01/rdf-schema#label |
Fucosyltransferase 2
|
| gptkbp:involves |
glycosylation
host-microbe interactions mucin biosynthesis |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19
19q13.33 |
| gptkbp:mutationAssociatedWith |
gptkb:Helicobacter_pylori_infection
gptkb:Crohn's_disease type 1 diabetes ulcerative colitis non-functional enzyme leads to non-secretor phenotype susceptibility to norovirus infection |
| gptkbp:OMIM |
182100
|
| gptkbp:orthologInMouse |
Fut2
|
| gptkbp:proteinFamily |
gptkb:glycosyltransferase_family_11
|
| gptkbp:related_to_blood_group |
gptkb:ABO_blood_group_system
Lewis blood group system |
| gptkbp:UniProtID |
gptkb:Q10981
|
| gptkbp:bfsParent |
gptkb:FUT2_gene
|
| gptkbp:bfsLayer |
7
|