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gptkbp:instanceOf
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gptkb:enzyme
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gptkbp:alternativeName
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gptkb:SE_gene
gptkb:Secretor_gene
gptkb:FUT2_gene
H blood group precursor fucosyltransferase
Secretor type alpha(1,2)fucosyltransferase
alpha(1,2)fucosyltransferase 2
galactoside 2-alpha-L-fucosyltransferase 2
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gptkbp:associated_with_phenotype
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secretor status
non-secretor status
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gptkbp:biologicalProcess
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gptkb:immune_response
protein glycosylation
cell-cell recognition
fucosyltransferase activity
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gptkbp:encodes
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gptkb:alpha(1,2)fucosyltransferase
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gptkbp:Entrez_Gene_ID
|
2524
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gptkbp:enzymeCommissionNumber
|
2.4.1.69
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gptkbp:expressedIn
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gastrointestinal tract
salivary glands
epithelial cells
respiratory tract
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gptkbp:foundIn
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gptkb:Homo_sapiens
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gptkbp:function
|
determines secretor status in humans
catalyzes the transfer of fucose to oligosaccharides
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gptkbp:gene
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gptkb:FUT2
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gptkbp:geneType
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protein-coding
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gptkbp:HGNC_ID
|
4017
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gptkbp:involves
|
glycosylation
host-microbe interactions
mucin biosynthesis
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gptkbp:locatedOnChromosome
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gptkb:chromosome_19
19q13.33
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gptkbp:mutationAssociatedWith
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gptkb:Helicobacter_pylori_infection
gptkb:Crohn's_disease
type 1 diabetes
ulcerative colitis
non-functional enzyme leads to non-secretor phenotype
susceptibility to norovirus infection
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gptkbp:OMIM
|
182100
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gptkbp:orthologInMouse
|
Fut2
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gptkbp:proteinFamily
|
gptkb:glycosyltransferase_family_11
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gptkbp:related_to_blood_group
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gptkb:ABO_blood_group_system
Lewis blood group system
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gptkbp:UniProtID
|
gptkb:Q10981
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gptkbp:bfsParent
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gptkb:FUT2_gene
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gptkbp:bfsLayer
|
7
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https://www.w3.org/2000/01/rdf-schema#label
|
Fucosyltransferase 2
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