|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:SE_gene
gptkb:Secretor_gene
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Helicobacter_pylori_infection
autoimmune diseases
inflammatory bowel disease
megaloblastic anemia
Norwalk virus resistance
microbiome composition
susceptibility to infections
|
|
gptkbp:biologicalProcess
|
glycosylation
transferase activity
|
|
gptkbp:cellularComponent
|
gptkb:Golgi_apparatus
|
|
gptkbp:clinicalTrialPhase
|
genotyping for secretor status
|
|
gptkbp:discoveredBy
|
gptkb:Yamamoto_et_al.
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:encodes
|
gptkb:alpha(1,2)fucosyltransferase
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000176920
gptkb:rs1047781
gptkb:rs601338
2524
|
|
gptkbp:expressedIn
|
gastrointestinal tract
salivary glands
epithelial cells
|
|
gptkbp:fullName
|
gptkb:fucosyltransferase_2
|
|
gptkbp:function
|
synthesizes H antigen on mucosal surfaces and in secretions
|
|
gptkbp:HGNC_ID
|
gptkb:FUT2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
FUT2 gene
|
|
gptkbp:length
|
2 exons
|
|
gptkbp:locatedOnChromosome
|
19
19q13.33
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Crohn's_disease
type 1 diabetes
vitamin B12 deficiency
increased susceptibility to Norovirus infection
non-secretor phenotype
|
|
gptkbp:OMIM
|
182100
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Pan_troglodytes
|
|
gptkbp:product
|
gptkb:Fucosyltransferase_2
|
|
gptkbp:proteinFamily
|
gptkb:glycosyltransferase_family_11
|
|
gptkbp:regulates
|
transcriptional regulation
|
|
gptkbp:relatedTo
|
gptkb:ABO_blood_group_system
secretor status
|
|
gptkbp:relatedTrait
|
non-secretor phenotype
secretor phenotype
|
|
gptkbp:UniProtID
|
gptkb:Q10981
|
|
gptkbp:bfsParent
|
gptkb:HH_blood_group
|
|
gptkbp:bfsLayer
|
6
|