|
gptkbp:instanceOf
|
gptkb:chemical_compound
|
|
gptkbp:application
|
synthesis of aromatic hydrocarbons
synthesis of aromatic ketones
|
|
gptkbp:commonCatalyst
|
gptkb:zinc_chloride
gptkb:aluminum_chloride
gptkb:ferric_chloride
|
|
gptkbp:discoveredIn
|
1877
|
|
gptkbp:field
|
organic chemistry
|
|
gptkbp:hasType
|
gptkb:Friedel–Crafts_acylation
gptkb:Friedel–Crafts_alkylation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Friedel–Crafts reaction
|
|
gptkbp:limitation
|
carbocation rearrangement
inapplicable to anilines
inapplicable to deactivated aromatics
polyalkylation
|
|
gptkbp:namedAfter
|
gptkb:James_Crafts
gptkb:Charles_Friedel
|
|
gptkbp:notableExample
|
gptkb:Friedel–Crafts_acylation_of_benzene
gptkb:Friedel–Crafts_benzylation
|
|
gptkbp:product
|
alkylated aromatic compound
acylated aromatic compound
|
|
gptkbp:reactant
|
gptkb:acyl_halide
alkyl halide
aromatic compound
|
|
gptkbp:reactionMechanism
|
gptkb:electrophilic_aromatic_substitution
|
|
gptkbp:usesCatalyst
|
gptkb:Lewis_acid
|
|
gptkbp:bfsParent
|
gptkb:Organic_Chemistry
gptkb:Charles_Friedel
|
|
gptkbp:bfsLayer
|
6
|