Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:application |
synthesis of aromatic ketones
|
| gptkbp:byproduct |
hydrogen chloride
|
| gptkbp:category |
name reaction
carbon–carbon bond forming reaction |
| gptkbp:commonCatalyst |
gptkb:aluminum_chloride
|
| gptkbp:firstReported |
1877
|
| https://www.w3.org/2000/01/rdf-schema#label |
Friedel–Crafts acylation
|
| gptkbp:limitation |
deactivated aromatic rings react poorly
polyacylation is rare |
| gptkbp:mechanismOfAction |
formation of acylium ion
|
| gptkbp:namedAfter |
gptkb:James_Crafts
gptkb:Charles_Friedel |
| gptkbp:notRecommendedFor |
aromatic amines
aromatic nitro compounds |
| gptkbp:produces |
aryl ketone
|
| gptkbp:relatedTo |
gptkb:Friedel–Crafts_alkylation
|
| gptkbp:solvent |
carbon disulfide
dichloromethane |
| gptkbp:substrate |
aromatic compound
|
| gptkbp:type |
gptkb:electrophilic_aromatic_substitution
|
| gptkbp:usesCatalyst |
gptkb:Lewis_acid
|
| gptkbp:usesReagent |
acid anhydride
acyl chloride |
| gptkbp:bfsParent |
gptkb:Wohl–Fittig_reaction
gptkb:Friedel–Crafts_reaction |
| gptkbp:bfsLayer |
7
|