electrophilic aromatic substitution
GPTKB entity
Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:activatingGroup |
electron-donating group
|
| gptkbp:deactivatingGroup |
electron-withdrawing group
|
| gptkbp:example |
gptkb:Friedel–Crafts_acylation
gptkb:Friedel–Crafts_alkylation nitration halogenation sulfonation |
| https://www.w3.org/2000/01/rdf-schema#label |
electrophilic aromatic substitution
|
| gptkbp:importantFor |
organic chemistry
|
| gptkbp:involves |
aromatic compound
electrophile |
| gptkbp:mechanismOfAction |
formation of arenium ion intermediate
|
| gptkbp:numberOfStages |
attack of electrophile on aromatic ring
|
| gptkbp:preserves |
aromaticity (after substitution)
|
| gptkbp:rateDependsOn |
nature of substituents on aromatic ring
|
| gptkbp:regioselectivity |
para
meta ortho |
| gptkbp:result |
substituted aromatic compound
|
| gptkbp:step |
loss of proton to restore aromaticity
|
| gptkbp:bfsParent |
gptkb:Zincke_nitration
gptkb:Friedel–Crafts_reaction gptkb:Kolbe-Schmitt_reaction |
| gptkbp:bfsLayer |
7
|