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Fibroblast growth factor receptor 1
URI:
https://gptkb.org/entity/Fibroblast_growth_factor_receptor_1
GPTKB entity
Statements (53)
Predicate
Object
gptkbp:instanceOf
gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alternativeName
gptkb:CEK
gptkb:FLG
gptkb:CD331
Epidermal growth factor receptor 2
FGFR-1
bFGF receptor
gptkbp:associatedWith
gptkb:cancer
gptkb:Kallmann_syndrome
gptkb:Pfeiffer_syndrome
gptkb:osteoglophonic_dysplasia
gptkbp:biologicalProcess
cell proliferation
signal transduction
MAPK cascade
protein tyrosine kinase activity
gptkbp:cellularComponent
gptkb:plasma_membrane
gptkbp:domain
immunoglobulin-like domain
tyrosine kinase domain
gptkbp:Entrez_Gene_ID
ENSG00000077782
gptkbp:expressedIn
gptkb:peripheral_blood_leukocyte
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
brain
heart
liver
spleen
colon
pancreas
gptkbp:formsComplexWith
FGF ligand
heparan sulfate proteoglycan
gptkbp:function
cell differentiation
angiogenesis
cell growth regulation
gptkbp:gene
gptkb:FGFR1
gptkbp:HGNC_ID
HGNC:3688
https://www.w3.org/2000/01/rdf-schema#label
Fibroblast growth factor receptor 1
gptkbp:ligand
fibroblast growth factor
gptkbp:locatedOnChromosome
8p11.23
gptkbp:mutationAssociatedWith
developmental disorders
oncogenesis
gptkbp:OMIM
136350
gptkbp:orthologInMouse
gptkb:Fgfr1
gptkbp:phosphorylates
tyrosine residue
gptkbp:UniProtID
P11362
gptkbp:bfsParent
gptkb:FGFR1
gptkbp:bfsLayer
6