Fibroblast growth factor receptor 1

GPTKB entity

Statements (53)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:protein
gptkbp:alternativeName gptkb:CEK
gptkb:FLG
gptkb:CD331
Epidermal growth factor receptor 2
FGFR-1
bFGF receptor
gptkbp:associatedWith gptkb:cancer
gptkb:Kallmann_syndrome
gptkb:Pfeiffer_syndrome
gptkb:osteoglophonic_dysplasia
gptkbp:biologicalProcess cell proliferation
signal transduction
MAPK cascade
protein tyrosine kinase activity
gptkbp:cellularComponent gptkb:plasma_membrane
gptkbp:domain immunoglobulin-like domain
tyrosine kinase domain
gptkbp:Entrez_Gene_ID ENSG00000077782
gptkbp:expressedIn gptkb:peripheral_blood_leukocyte
gptkb:cancer
gptkb:skeletal_muscle
gptkb:kidney
gptkb:placenta
gptkb:prostate
gptkb:small_intestine
gptkb:testis
gptkb:thymus
brain
heart
liver
spleen
colon
pancreas
gptkbp:formsComplexWith FGF ligand
heparan sulfate proteoglycan
gptkbp:function cell differentiation
angiogenesis
cell growth regulation
gptkbp:gene gptkb:FGFR1
gptkbp:HGNC_ID HGNC:3688
https://www.w3.org/2000/01/rdf-schema#label Fibroblast growth factor receptor 1
gptkbp:ligand fibroblast growth factor
gptkbp:locatedOnChromosome 8p11.23
gptkbp:mutationAssociatedWith developmental disorders
oncogenesis
gptkbp:OMIM 136350
gptkbp:orthologInMouse gptkb:Fgfr1
gptkbp:phosphorylates tyrosine residue
gptkbp:UniProtID P11362
gptkbp:bfsParent gptkb:FGFR1
gptkbp:bfsLayer 6