Statements (46)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:CD32
gptkb:FcγR CD16 CD64 |
| gptkbp:binds |
Fc region of IgG antibodies
|
| gptkbp:discoveredIn |
1970s
|
| gptkbp:encodedBy |
gptkb:FCGR2A_gene
gptkb:FCGR2B_gene gptkb:FCGR2C_gene FCGR3A gene FCGR3B gene FCGR1A gene |
| gptkbp:foundIn |
gptkb:natural_killer_cells
gptkb:B_cells gptkb:mast_cells gptkb:eosinophils dendritic cells macrophages immune cells neutrophils |
| gptkbp:function |
immune cell activation
immune cell inhibition |
| https://www.w3.org/2000/01/rdf-schema#label |
Fc gamma receptors
|
| gptkbp:involvedIn |
autoimmune diseases
infectious disease response allergic reactions |
| gptkbp:medium |
phagocytosis
antibody-dependent cellular cytotoxicity inflammatory responses |
| gptkbp:modulatedBy |
glycosylation
polymorphisms |
| gptkbp:regulates |
immune complex clearance
inflammatory signaling |
| gptkbp:species |
gptkb:human
gptkb:mouse |
| gptkbp:structure |
transmembrane protein
extracellular Ig-like domains |
| gptkbp:target |
therapeutic antibodies
|
| gptkbp:type |
FcγRI
FcγRII FcγRIII FcγRIV |
| gptkbp:bfsParent |
gptkb:IgG1_kappa
gptkb:FCGR_genes |
| gptkbp:bfsLayer |
7
|