FATC domain

GPTKB entity

Statements (20)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:associatedWith gptkb:mTOR_protein
ATM protein
ATR protein
DNA-PKcs protein
SMG1 protein
gptkbp:conservedIn eukaryotes
gptkbp:foundIn gptkb:PIKK_family_proteins
gptkbp:function protein-protein interaction
protein stability
https://www.w3.org/2000/01/rdf-schema#label FATC domain
gptkbp:InterPro IPR003591
gptkbp:length ~30-35 amino acids
gptkbp:locatedIn C-terminus of PIKK proteins
gptkbp:mutationAssociatedWith loss of kinase activity
gptkbp:proteinFamily PF02260
gptkbp:requires kinase activity of PIKK proteins
gptkbp:structure predicted to form a compact fold
gptkbp:bfsParent gptkb:ATM_kinase
gptkbp:bfsLayer 7