|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
7
|
|
gptkbp:bfsParent
|
gptkb:Esomeprazole
|
|
gptkbp:activities
|
inhibits proton pump in gastric parietal cells
|
|
gptkbp:approves
|
gptkb:legislation
gptkb:United_States
|
|
gptkbp:brand
|
gptkb:Nexium
Esomeprazole Strontium
|
|
gptkbp:category
|
Category C
|
|
gptkbp:class
|
gptkb:railway_station
|
|
gptkbp:clinical_trial
|
Phase III
|
|
gptkbp:contraindication
|
severe liver disease
hypersensitivity to esomeprazole
|
|
gptkbp:dosage_form
|
10 mg
20 mg
30 mg
40 mg
|
|
gptkbp:duration
|
24 hours
|
|
gptkbp:form
|
tablets
injection
capsules
|
|
gptkbp:formulation
|
magnesium salt
|
|
gptkbp:healthcare
|
gptkb:2001
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Esomeprazole magnesium
|
|
gptkbp:ingredients
|
gptkb:esomeprazole
C17 H18 N3 O3 S
|
|
gptkbp:interacts_with
|
gptkb:methotrexate
gptkb:clopidogrel
gptkb:digoxin
gptkb:warfarin
|
|
gptkbp:is_atype_of
|
A02 B C05
|
|
gptkbp:is_used_for
|
treating gastroesophageal reflux disease (GERD)
treating peptic ulcers
treating Zollinger-Ellison syndrome
|
|
gptkbp:lifespan
|
about 1.3 hours
|
|
gptkbp:manager
|
oral
|
|
gptkbp:marketed_as
|
gptkb:temple
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:premiered_on
|
1 hour
|
|
gptkbp:side_effect
|
gptkb:healthcare_organization
headache
nausea
abdominal pain
diarrhea
liver damage
bone fractures
gastrointestinal infections
low magnesium levels
|
|
gptkbp:storage
|
room temperature
protected from moisture
|
|
gptkbp:type_of
|
161796-78-7
|