Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:cancer
Malignant neoplasm |
| gptkbp:associatedWith |
Estrogen exposure
|
| gptkbp:canMetastasizeTo |
gptkb:Peritoneum
Lungs Liver Lymph nodes |
| gptkbp:diagnosedBy |
Histopathology
Imaging studies Endometrial biopsy |
| gptkbp:differentialDiagnosis |
gptkb:Clear_cell_carcinoma
gptkb:Carcinosarcoma gptkb:Serous_carcinoma |
| gptkbp:grades |
Grade 1 (well differentiated)
Grade 2 (moderately differentiated) Grade 3 (poorly differentiated) |
| gptkbp:histology |
Glandular pattern resembling endometrial tissue
|
| https://www.w3.org/2000/01/rdf-schema#label |
Endometrioid adenocarcinoma
|
| gptkbp:ICD-10_code |
gptkb:C54.1
|
| gptkbp:molecularFeature |
gptkb:KRAS_mutation
PTEN mutation PIK3CA mutation Microsatellite instability |
| gptkbp:mostCommonSite |
Endometrium
|
| gptkbp:occurredIn |
gptkb:Fallopian_tube
Cervix Ovary Vagina |
| gptkbp:originatedIn |
Glandular epithelial cells
|
| gptkbp:prognosis |
Generally favorable if detected early
|
| gptkbp:riskFactor |
gptkb:Lynch_syndrome
gptkb:Polycystic_ovary_syndrome Obesity Early menarche Late menopause Nulliparity Unopposed estrogen therapy |
| gptkbp:SNOMED_CT_code |
254837009
|
| gptkbp:subspecies |
Endocervical endometrioid adenocarcinoma
Endometrial endometrioid adenocarcinoma Ovarian endometrioid adenocarcinoma |
| gptkbp:symptom |
Abnormal uterine bleeding
Pelvic pain Postmenopausal bleeding |
| gptkbp:treatment |
radiation therapy
Surgery Chemotherapy Hormonal therapy |
| gptkbp:bfsParent |
gptkb:Endometrial_cancer
|
| gptkbp:bfsLayer |
7
|