Emend

GPTKB entity

Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:approvalYear 2003
gptkbp:ATCCode gptkb:A04AD12
gptkbp:CASNumber gptkb:170729-80-3
gptkbp:chemicalFormula C23H21F7N4O3
gptkbp:drugInteraction gptkb:rifampin
gptkb:warfarin
gptkb:dexamethasone
gptkb:ketoconazole
oral contraceptives
gptkbp:form capsule
powder for injection
gptkbp:genericName gptkb:aprepitant
https://www.w3.org/2000/01/rdf-schema#label Emend
gptkbp:legalStatus prescription only
gptkbp:manufacturer gptkb:Merck_&_Co.
gptkbp:mechanismOfAction neurokinin-1 (NK1) receptor antagonist
gptkbp:pregnancyCategory B
gptkbp:routeOfAdministration oral
intravenous
gptkbp:sideEffect diarrhea
anorexia
constipation
fatigue
headache
hiccups
gptkbp:usedFor prevention of postoperative nausea and vomiting
prevention of chemotherapy-induced nausea and vomiting
gptkbp:bfsParent gptkb:Merck_&_Co.
gptkbp:bfsLayer 4