Statements (30)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
|
gptkbp:approvalYear |
2003
|
gptkbp:ATCCode |
gptkb:A04AD12
|
gptkbp:CASNumber |
gptkb:170729-80-3
|
gptkbp:chemicalFormula |
C23H21F7N4O3
|
gptkbp:drugInteraction |
gptkb:rifampin
gptkb:warfarin gptkb:dexamethasone gptkb:ketoconazole oral contraceptives |
gptkbp:form |
capsule
powder for injection |
gptkbp:genericName |
gptkb:aprepitant
|
https://www.w3.org/2000/01/rdf-schema#label |
Emend
|
gptkbp:legalStatus |
prescription only
|
gptkbp:manufacturer |
gptkb:Merck_&_Co.
|
gptkbp:mechanismOfAction |
neurokinin-1 (NK1) receptor antagonist
|
gptkbp:pregnancyCategory |
B
|
gptkbp:routeOfAdministration |
oral
intravenous |
gptkbp:sideEffect |
diarrhea
anorexia constipation fatigue headache hiccups |
gptkbp:usedFor |
prevention of postoperative nausea and vomiting
prevention of chemotherapy-induced nausea and vomiting |
gptkbp:bfsParent |
gptkb:Merck_&_Co.
|
gptkbp:bfsLayer |
4
|