Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:activatedBy |
oncogenic pathways
|
| gptkbp:affects |
gene expression
|
| gptkbp:associatedWith |
gptkb:Ewing_sarcoma
|
| gptkbp:chromosomalTranslocation |
gptkb:t(11;22)(q24;q12)
|
| gptkbp:compatibleWith |
normal tissues
|
| gptkbp:discoveredIn |
1992
|
| gptkbp:encodes |
chimeric transcription factor
|
| gptkbp:expressedIn |
Ewing sarcoma cells
|
| gptkbp:fusionPartner1 |
gptkb:EWSR1
|
| gptkbp:fusionPartner2 |
gptkb:FLI1
|
| https://www.w3.org/2000/01/rdf-schema#label |
EWSR1-FLI1
|
| gptkbp:mergedInto |
gptkb:EWSR1
gptkb:FLI1 |
| gptkbp:molecularWeight |
~68 kDa
|
| gptkbp:regulates |
gptkb:ETS_family
apoptosis cell differentiation cell proliferation |
| gptkbp:target |
therapeutic research
|
| gptkbp:usedAs |
diagnostic marker
|
| gptkbp:bfsParent |
gptkb:Ewing's_sarcoma
gptkb:t(11;22)(q24;q12) |
| gptkbp:bfsLayer |
7
|