|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:ESRB
NR3A2
ER-beta
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:binds
|
estrogen
|
|
gptkbp:chromosomeArm
|
14q23.2
|
|
gptkbp:discoveredBy
|
gptkb:Jan-Åke_Gustafsson
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodes
|
Estrogen receptor beta protein
|
|
gptkbp:Entrez_Gene_ID
|
2100
ENSG00000140009
|
|
gptkbp:expressedIn
|
gptkb:cancer
gptkb:prostate
gptkb:testis
brain
cardiovascular tissue
|
|
gptkbp:fullName
|
gptkb:Estrogen_receptor_beta
|
|
gptkbp:function
|
transcription factor
nuclear receptor
|
|
gptkbp:HGNC_ID
|
3468
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ESR2 gene
|
|
gptkbp:locatedOnChromosome
|
14
|
|
gptkbp:MIM_number
|
601663
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
infertility
endometriosis
|
|
gptkbp:OMIM
|
601663
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Esr2
|
|
gptkbp:product
|
gptkb:Estrogen_receptor_beta
|
|
gptkbp:proteinFamily
|
nuclear receptor subfamily 3 group A member 2
|
|
gptkbp:RefSeq
|
NM_001437
|
|
gptkbp:regulates
|
apoptosis
cell proliferation
gene expression
reproductive system development
|
|
gptkbp:relatedTo
|
gptkb:cancer
prostate cancer
cardiovascular system
ovarian function
|
|
gptkbp:symbol
|
gptkb:ESR2
|
|
gptkbp:target
|
hormone therapy
phytoestrogens
selective estrogen receptor modulators
|
|
gptkbp:UniProtID
|
gptkb:Q92731
|
|
gptkbp:bfsParent
|
gptkb:KR-ERB
gptkb:Estrogen_receptor
|
|
gptkbp:bfsLayer
|
7
|