EC 3.2.1.23

GPTKB entity

Statements (42)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:associatedWith gptkb:GLA
gptkbp:CASNumber 9025-35-8
gptkbp:catalyzes hydrolysis of terminal alpha-galactosyl moieties in alpha-galactosides
gptkbp:cofactor none required
gptkbp:commercialSource gptkb:Aspergillus_niger
almonds
green coffee beans
gptkbp:deficiencyCauses gptkb:Fabry_disease
gptkbp:EC_number 3.2.1.23
gptkbp:enzyme gptkb:alpha-galactosidase
gptkbp:foundIn gptkb:Bacteria
animals
plants
gptkbp:GO GO:0004557
https://www.w3.org/2000/01/rdf-schema#label EC 3.2.1.23
gptkbp:inhibitedBy galactose
AgNO3
HgCl2
gptkbp:locatedIn lysosome (in animals)
gptkbp:molecularWeight ~46 kDa (human)
gptkbp:optimum_pH 4.5-6.0
gptkbp:optimumTemperature 37°C
gptkbp:otherName alpha-galactoside galactohydrolase
melibiase
melibiase I
gptkbp:PDB 1R46
gptkbp:product glucose
sucrose
fructose
galactose
gptkbp:structure homodimer (in some species)
gptkbp:substrate melibiose
raffinose
stachyose
gptkbp:systematicName alpha-D-galactoside galactohydrolase
gptkbp:UniProtID P06280
gptkbp:usedIn food industry
diagnosis of Fabry disease
removal of raffinose family oligosaccharides from legumes
gptkbp:bfsParent gptkb:lacZ
gptkbp:bfsLayer 7