Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:catalyzes |
transfer of ubiquitin from E2 to substrate
|
| gptkbp:do_not_require |
zinc ions for structure
|
| gptkbp:domain |
U-box domain
|
| gptkbp:example |
AtPUB family (Arabidopsis thaliana)
CHIP (C-terminus of Hsc70-Interacting Protein) PRP19 UBR5 |
| gptkbp:firstDescribed |
late 1990s
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:function |
ubiquitin ligase activity
|
| gptkbp:GO_term |
GO:0061630 (ubiquitin protein ligase activity)
|
| https://www.w3.org/2000/01/rdf-schema#label |
U-box E3 ligases
|
| gptkbp:involves |
ubiquitination
|
| gptkbp:relatedTo |
gptkb:RING_finger_E3_ligases
|
| gptkbp:role |
cell signaling
protein quality control stress response |
| gptkbp:structural_feature |
U-box domain is similar to RING domain but lacks zinc coordination
|
| gptkbp:bfsParent |
gptkb:E3_ubiquitin-protein_ligase
|
| gptkbp:bfsLayer |
7
|