E3 (dihydrolipoamide dehydrogenase)
GPTKB entity
Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:DLD
NAD+-dependent dihydrolipoamide dehydrogenase lipoamide dehydrogenase |
| gptkbp:biologicalProcess |
oxidoreductase activity
|
| gptkbp:catalyzes |
oxidation of dihydrolipoamide to lipoamide
|
| gptkbp:cofactor |
gptkb:FAD
NAD+ |
| gptkbp:component |
gptkb:branched-chain_alpha-keto_acid_dehydrogenase_complex
gptkb:pyruvate_dehydrogenase_complex gptkb:alpha-ketoglutarate_dehydrogenase_complex |
| gptkbp:EC_number |
1.8.1.4
|
| gptkbp:foundIn |
mitochondria
|
| gptkbp:gene |
gptkb:DLD
|
| https://www.w3.org/2000/01/rdf-schema#label |
E3 (dihydrolipoamide dehydrogenase)
|
| gptkbp:locatedOnChromosome |
7q31-q32
|
| gptkbp:mutationAssociatedWith |
dihydrolipoamide dehydrogenase deficiency
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:product |
gptkb:H+
gptkb:NADH lipoamide |
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
dihydrolipoamide
|
| gptkbp:UniProtID |
P09622
|
| gptkbp:bfsParent |
gptkb:pyruvate_dehydrogenase_complex
|
| gptkbp:bfsLayer |
7
|