alpha-ketoglutarate dehydrogenase complex
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
2-oxoglutarate dehydrogenase complex
KGDHC OGDC |
| gptkbp:associatedWith |
alpha-ketoglutarate dehydrogenase deficiency
|
| gptkbp:catalyzes |
conversion of alpha-ketoglutarate to succinyl-CoA
|
| gptkbp:cofactor |
gptkb:CoA
gptkb:FAD NAD+ thiamine pyrophosphate lipoic acid |
| gptkbp:component |
E1 (alpha-ketoglutarate dehydrogenase)
E2 (dihydrolipoyl succinyltransferase) E3 (dihydrolipoyl dehydrogenase) |
| gptkbp:EC_number |
1.2.4.2
|
| gptkbp:gene |
gptkb:DLD
gptkb:OGDH DLST |
| https://www.w3.org/2000/01/rdf-schema#label |
alpha-ketoglutarate dehydrogenase complex
|
| gptkbp:inhibitedBy |
gptkb:NADH
gptkb:succinyl-CoA arsenite |
| gptkbp:location |
mitochondrial matrix
|
| gptkbp:pathway |
citric acid cycle
|
| gptkbp:bfsParent |
gptkb:alpha-ketoglutarate_dehydrogenase
gptkb:succinyl-CoA |
| gptkbp:bfsLayer |
6
|