Duffy antigen receptor for chemokines

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:gene
gptkbp:alsoKnownAs	gptkb:ACKR1 gptkb:DARC CD234
gptkbp:alternativeSplicing	yes
gptkbp:antigenicDeterminants	Fya Fyb Fy10 Fy11 Fy12 Fy3 Fy4 Fy5 Fy6 Fy7 Fy8 Fy9 FyX
gptkbp:associatedWith	inflammatory diseases benign ethnic neutropenia
gptkbp:binds	chemokines
gptkbp:bloodGroupSystem	gptkb:Duffy_blood_group_system
gptkbp:discoveredBy	Marion Duffy
gptkbp:encodedBy	gptkb:ACKR1_gene
gptkbp:Entrez_Gene_ID	2532
gptkbp:expressedIn	red blood cells endothelial cells
gptkbp:firstDescribed	1950
gptkbp:function	gptkb:blood_group_antigen gptkb:chemokine_receptor
gptkbp:geneType	protein-coding
gptkbp:HGNC_ID	HGNC:251
gptkbp:locatedOnChromosome	chromosome 1
gptkbp:molecularWeight	~35 kDa
gptkbp:mutationAssociatedWith	Fy(a-b-) phenotype Duffy-null phenotype
gptkbp:OMIM	110700
gptkbp:orthologIn	gptkb:Mus_musculus gptkb:Pan_troglodytes
gptkbp:significance	malaria resistance Plasmodium vivax entry receptor
gptkbp:species	gptkb:Homo_sapiens
gptkbp:structure	seven-transmembrane protein
gptkbp:transmembraneDomains	7
gptkbp:UniProtID	Q16570
gptkbp:bfsParent	gptkb:CD296 gptkb:ACKR1_gene
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	Duffy antigen receptor for chemokines