Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
gptkb:DARC
gptkb:Duffy_antigen_receptor_for_chemokines |
| gptkbp:associatedWith |
gptkb:Duffy_blood_group_system
malaria resistance |
| gptkbp:discoveredBy |
Duffy (1950)
|
| gptkbp:encodes |
Atypical chemokine receptor 1 protein
|
| gptkbp:Entrez_Gene_ID |
2532
|
| gptkbp:expressedIn |
endothelial cells
erythrocytes |
| gptkbp:function |
binds chemokines
acts as a chemokine decoy receptor |
| gptkbp:HGNC_ID |
HGNC:2512
|
| https://www.w3.org/2000/01/rdf-schema#label |
ACKR1
|
| gptkbp:involvedIn |
inflammatory response
leukocyte trafficking |
| gptkbp:length |
336 amino acids
|
| gptkbp:locatedOnChromosome |
1
1q23.2 |
| gptkbp:molecularWeight |
35 kDa
|
| gptkbp:mutationAssociatedWith |
Duffy-negative phenotype
protection against Plasmodium vivax infection |
| gptkbp:numberOfExons |
2
|
| gptkbp:OMIM |
110700
|
| gptkbp:orthologInMouse |
Ackr1
|
| gptkbp:transmembraneDomains |
yes
|
| gptkbp:UniProtID |
Q16570
|
| gptkbp:bfsParent |
gptkb:CD296
gptkb:Duffy_blood_group_system |
| gptkbp:bfsLayer |
8
|