Dihydrotestosterone (DHT)

URI: https://gptkb.org/entity/Dihydrotestosterone_(DHT)
GPTKB entity
Statements (49)
Predicate Object
gptkbp:instanceOf hormone
androgen
gptkbp:affects acne
libido
spermatogenesis
voice deepening
muscle mass
facial hair growth
scalp hair loss
secondary sexual characteristics
gptkbp:associatedWith gptkb:benign_prostatic_hyperplasia
prostate cancer
male pattern baldness
gptkbp:binds gptkb:androgen_receptor
gptkbp:CASNumber 521-18-6
gptkbp:category gptkb:androstane
hormone
anabolic steroid
endogenous androgen
gptkbp:chemicalFormula C19H30O2
gptkbp:derivedFrom testosterone
gptkbp:foundIn humans
other mammals
https://www.w3.org/2000/01/rdf-schema#label Dihydrotestosterone (DHT)
gptkbp:inhibitedBy gptkb:dutasteride
gptkb:finasteride
gptkbp:IUPACName gptkb:17β-hydroxy-5α-androstan-3-one
gptkbp:meltingPoint 178–180 °C
gptkbp:MeSH_ID gptkb:D004110
gptkbp:metabolism gptkb:3α-hydroxysteroid_dehydrogenase
testosterone
gptkbp:molecularWeight 290.44 g/mol
gptkbp:morePotentThan testosterone
gptkbp:producedBy gptkb:prostate
adrenal glands
testes
hair follicles
gptkbp:PubChem_CID gptkb:CHEMBL1179
gptkb:DB00624
gptkb:CHEBI:16446
10635
gptkbp:role male sexual development
sebaceous gland activity
hair growth regulation
prostate development
gptkbp:synthesisType gptkb:5α-reductase
gptkbp:UNII GB71M88MYZ
gptkbp:bfsParent gptkb:DH
gptkbp:bfsLayer 6