Deleted in Pancreatic Carcinoma, locus 4
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:abbreviation |
gptkb:DPC4
|
| gptkbp:alsoKnownAs |
gptkb:SMAD4
|
| gptkbp:associatedWith |
gptkb:juvenile_polyposis_syndrome
gptkb:hereditary_hemorrhagic_telangiectasia pancreatic cancer |
| gptkbp:discoveredBy |
Y. Shimizu et al.
|
| gptkbp:discoveredIn |
1996
|
| gptkbp:encodes |
gptkb:SMAD4_protein
|
| gptkbp:Entrez_Gene_ID |
4089
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
gptkb:tumor_suppressor
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:involves |
gptkb:TGF-beta_signaling_pathway
|
| gptkbp:locatedOnChromosome |
gptkb:18q21.2
gptkb:chromosome_18 |
| gptkbp:mutationAssociatedWith |
loss of function mutations lead to cancer
|
| gptkbp:OMIM |
600993
|
| gptkbp:orthologInMouse |
gptkb:Smad4
|
| gptkbp:UniProtID |
gptkb:Q13485
|
| gptkbp:bfsParent |
gptkb:DPC4
|
| gptkbp:bfsLayer |
7
|
| http://www.w3.org/2000/01/rdf-schema#label |
Deleted in Pancreatic Carcinoma, locus 4
|