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gptkbp:instanceOf
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gptkb:protein
gptkb:enzyme
|
|
gptkbp:alternativeName
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gptkb:POLQ
Pol θ
Polymerase theta
|
|
gptkbp:biologicalProcess
|
ATPase activity
DNA-directed DNA polymerase activity
|
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gptkbp:cellularComponent
|
gptkb:nucleus
|
|
gptkbp:discoveredBy
|
1999
|
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gptkbp:EC_number
|
2.7.7.7
|
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gptkbp:encodedBy
|
gptkb:POLQ_gene
|
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gptkbp:foundIn
|
gptkb:Homo_sapiens
|
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gptkbp:function
|
DNA repair
translesion synthesis
alternative end-joining
|
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gptkbp:gene_ID_(human)
|
10721
|
|
gptkbp:GO_term
|
GO:0006281
GO:0003887
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DNA polymerase theta
|
|
gptkbp:involvedIn
|
double-strand break repair
microhomology-mediated end joining
|
|
gptkbp:length_(human)
|
2592 amino acids
|
|
gptkbp:locatedOnChromosome
|
3q13.31
|
|
gptkbp:OMIM
|
601937
|
|
gptkbp:role_in_cancer
|
genomic instability
chemoresistance
|
|
gptkbp:species
|
gptkb:human
gptkb:mouse
gptkb:Drosophila_melanogaster
|
|
gptkbp:structure
|
polymerase domain
helicase-like domain
|
|
gptkbp:UniProtID
|
gptkb:Q9H9Q4
|
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gptkbp:bfsParent
|
gptkb:helicase,_POLQ-like
|
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gptkbp:bfsLayer
|
7
|