Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
| gptkbp:activity |
3'-5' exonuclease activity
5'-3' DNA polymerase activity |
| gptkbp:component |
POLD1
POLD2 POLD3 POLD4 |
| gptkbp:discoveredBy |
1980s
|
| gptkbp:EC_number |
2.7.7.7
|
| gptkbp:function |
DNA repair
DNA replication |
| gptkbp:gene |
POLD1
POLD2 POLD3 POLD4 |
| https://www.w3.org/2000/01/rdf-schema#label |
DNA polymerase delta
|
| gptkbp:interactsWith |
gptkb:PCNA
replication factor C replication protein A |
| gptkbp:involvedIn |
lagging strand synthesis
Okazaki fragment processing |
| gptkbp:location |
gptkb:nucleus
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
immunodeficiency polymerase proofreading-associated polyposis |
| gptkbp:organism |
eukaryotes
|
| gptkbp:orthologIn |
yeast Pol3
|
| gptkbp:regulates |
gptkb:proliferating_cell_nuclear_antigen_(PCNA)
|
| gptkbp:requires |
genome stability
|
| gptkbp:subunit |
catalytic subunit
accessory subunits |
| gptkbp:bfsParent |
gptkb:PCNA
gptkb:PDIP46/SKAR |
| gptkbp:bfsLayer |
7
|