Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
KARAP
TYROBP Killer cell activating receptor-associated protein |
| gptkbp:discoveredIn |
1997
|
| gptkbp:domain |
gptkb:immunoreceptor_tyrosine-based_activation_motif_(ITAM)
|
| gptkbp:encodedBy |
TYROBP gene
|
| gptkbp:expressedIn |
gptkb:natural_killer_cells
gptkb:microglia myeloid cells |
| gptkbp:formsComplexWith |
cell surface receptors
|
| gptkbp:foundIn |
humans
mice |
| gptkbp:function |
signal transduction
|
| https://www.w3.org/2000/01/rdf-schema#label |
DAP12 adaptor protein
|
| gptkbp:interactsWith |
gptkb:TREM2
SIRPĪ²1 CD33-related Siglecs |
| gptkbp:involvedIn |
immune response
phagocytosis inflammatory signaling |
| gptkbp:locatedOnChromosome |
chromosome 19q13.12 (human)
|
| gptkbp:molecularWeight |
~12 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:Nasu-Hakola_disease
polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy |
| gptkbp:subcellularLocation |
gptkb:cell_membrane
gptkb:cytoplasm |
| gptkbp:bfsParent |
gptkb:NKp44
|
| gptkbp:bfsLayer |
8
|