Cu,Zn-superoxide dismutase

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:enzyme
gptkbp:alternativeName	gptkb:SOD1
gptkbp:associatedWith	amyotrophic lateral sclerosis
gptkbp:cofactor	copper zinc
gptkbp:discoveredBy	gptkb:Irwin_Fridovich gptkb:Joe_M._McCord
gptkbp:discoveredIn	1969
gptkbp:EC_number	1.15.1.1
gptkbp:Entrez_Gene_ID	6647 (human)
gptkbp:family	gptkb:superoxide_dismutase_family
gptkbp:function	catalyzes dismutation of superoxide radicals
gptkbp:gene	gptkb:SOD1
gptkbp:GO	gptkb:GO:0004784
gptkbp:inhibitedBy	gptkb:diethyldithiocarbamate cyanide
gptkbp:locatedOnChromosome	gptkb:21q22.11_(human)
gptkbp:location	gptkb:cytoplasm gptkb:mitochondrial_intermembrane_space
gptkbp:molecularWeight	32 kDa
gptkbp:mutationAssociatedWith	linked to familial ALS
gptkbp:OMIM	147450
gptkbp:organism	gptkb:Mus_musculus gptkb:Homo_sapiens
gptkbp:PDB	gptkb:1HL5
gptkbp:product	hydrogen peroxide oxygen
gptkbp:structure	homodimer
gptkbp:substrate	gptkb:superoxide_anion
gptkbp:UniProtID	gptkb:P00441
gptkbp:bfsParent	gptkb:superoxide_dismutase_[Cu-Zn]
gptkbp:bfsLayer	6
http://www.w3.org/2000/01/rdf-schema#label	Cu,Zn-superoxide dismutase