Coenzyme Q10

URI: https://gptkb.org/entity/Coenzyme_Q10

GPTKB entity

Statements (78)

Predicate	Object
gptkbp:instanceOf	gptkb:quinone gptkb:coenzyme
gptkbp:absorption	improved with fat
gptkbp:approvedBy	gptkb:Japan heart failure (Japan)
gptkbp:biosynthesized_from	gptkb:mevalonate_pathway gptkb:tyrosine
gptkbp:CASNumber	303-98-0
gptkbp:category	dietary supplements antioxidants quinones coenzymes mitochondrial proteins
gptkbp:chemicalFormula	C59H90O4
gptkbp:color	yellow to orange crystalline powder
gptkbp:compatibleWith	FDA (for any medical condition)
gptkbp:discoveredBy	gptkb:Frederick_L._Crane
gptkbp:discoveredIn	1957
gptkbp:eliminatedIn	feces urine (minor) biliary excretion
gptkbp:foundIn	mitochondria
gptkbp:function	gptkb:antioxidant ATP synthesis electron transport chain
gptkbp:halfLife	33 hours
gptkbp:hasChEMBL	CHEMBL275695
gptkbp:hasEINECSNumber	206-147-9
gptkbp:hasUNII	KJZ4T0802F
gptkbp:interactsWith	gptkb:warfarin beta-blockers statins chemotherapy drugs
gptkbp:IUPACName	2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
gptkbp:legalStatus	OTC (over-the-counter, supplement)
gptkbp:meltingPoint	48-52 °C
gptkbp:molecularWeight	863.34 g/mol
gptkbp:numberOfIsopreneUnits	10
gptkbp:otherName	gptkb:ubidecarenone ubiquinone
gptkbp:presentIn	gptkb:fish gptkb:meat gptkb:vegetable_oils gptkb:lettuce gptkb:kidney broccoli mackerel heart nuts soybeans peanuts liver whole grains sardines
gptkbp:PubChem_CID	DB09313 5281915 CHEBI:46245
gptkbp:routeOfAdministration	oral topical intravenous (rare)
gptkbp:sideEffect	nausea diarrhea loss of appetite rash insomnia
gptkbp:solubility	lipid-soluble
gptkbp:stable	degraded by light stable in oil
gptkbp:structureType	benzoquinone ring with isoprenoid side chain
gptkbp:usedAs	gptkb:dietary_supplement
gptkbp:usedFor	gptkb:statin-induced_myopathy heart failure migraine prevention
gptkbp:bfsParent	gptkb:Pregnacare_Him_&_Her_Conception gptkb:TruNature_CoQ10 gptkb:Lacura_Q10_Anti-Wrinkle_Cream
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	Coenzyme Q10