Statements (78)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:coenzyme
quinone |
| gptkbp:absorption |
improved with fat
|
| gptkbp:approvedBy |
gptkb:Japan
heart failure (Japan) |
| gptkbp:biosynthesized_from |
gptkb:mevalonate_pathway
gptkb:tyrosine |
| gptkbp:CASNumber |
303-98-0
|
| gptkbp:category |
dietary supplements
antioxidants quinones coenzymes mitochondrial proteins |
| gptkbp:chemicalFormula |
C59H90O4
|
| gptkbp:color |
yellow to orange crystalline powder
|
| gptkbp:compatibleWith |
FDA (for any medical condition)
|
| gptkbp:discoveredBy |
gptkb:Frederick_L._Crane
|
| gptkbp:discoveredIn |
1957
|
| gptkbp:eliminatedIn |
feces
urine (minor) biliary excretion |
| gptkbp:foundIn |
mitochondria
|
| gptkbp:function |
antioxidant
ATP synthesis electron transport chain |
| gptkbp:halfLife |
33 hours
|
| gptkbp:hasChEMBL |
CHEMBL275695
|
| gptkbp:hasEINECSNumber |
206-147-9
|
| gptkbp:hasUNII |
KJZ4T0802F
|
| https://www.w3.org/2000/01/rdf-schema#label |
Coenzyme Q10
|
| gptkbp:interactsWith |
gptkb:warfarin
beta-blockers statins chemotherapy drugs |
| gptkbp:IUPACName |
2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
|
| gptkbp:legalStatus |
OTC (over-the-counter, supplement)
|
| gptkbp:meltingPoint |
48-52 °C
|
| gptkbp:molecularWeight |
863.34 g/mol
|
| gptkbp:numberOfIsopreneUnits |
10
|
| gptkbp:otherName |
gptkb:ubidecarenone
ubiquinone |
| gptkbp:presentIn |
gptkb:fish
gptkb:meat gptkb:vegetable_oils gptkb:kidney broccoli mackerel heart lettuce nuts soybeans peanuts liver whole grains sardines |
| gptkbp:PubChem_CID |
DB09313
5281915 CHEBI:46245 |
| gptkbp:routeOfAdministration |
oral
topical intravenous (rare) |
| gptkbp:sideEffect |
nausea
diarrhea loss of appetite rash insomnia |
| gptkbp:solubility |
lipid-soluble
|
| gptkbp:stable |
degraded by light
stable in oil |
| gptkbp:structureType |
benzoquinone ring with isoprenoid side chain
|
| gptkbp:usedAs |
dietary supplement
|
| gptkbp:usedFor |
gptkb:statin-induced_myopathy
heart failure migraine prevention |
| gptkbp:bfsParent |
gptkb:Pregnacare_Him_&_Her_Conception
gptkb:TruNature_CoQ10 gptkb:Lacura_Q10_Anti-Wrinkle_Cream |
| gptkbp:bfsLayer |
7
|