statin-induced myopathy

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf medical condition
adverse drug reaction
gptkbp:canProgressTo rhabdomyolysis
gptkbp:causedBy statins
gptkbp:complication statin therapy
gptkbp:diagnosedBy clinical evaluation
creatine kinase test
gptkbp:firstDescribed 1990s
https://www.w3.org/2000/01/rdf-schema#label statin-induced myopathy
gptkbp:ICD-10_code G72.0
gptkbp:MeSH_ID D000071299
gptkbp:prevalence 1-10% of statin users
gptkbp:riskFactor genetic predisposition
hypothyroidism
older age
renal impairment
concomitant medications
high statin dose
gptkbp:symptom muscle pain
muscle weakness
elevated creatine kinase
muscle cramps
gptkbp:treatment dose reduction
coenzyme Q10 supplementation
statin discontinuation
switching statin
gptkbp:bfsParent gptkb:HMGCR
gptkbp:bfsLayer 7