Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
medical condition
adverse drug reaction |
gptkbp:canProgressTo |
rhabdomyolysis
|
gptkbp:causedBy |
statins
|
gptkbp:complication |
statin therapy
|
gptkbp:diagnosedBy |
clinical evaluation
creatine kinase test |
gptkbp:firstDescribed |
1990s
|
https://www.w3.org/2000/01/rdf-schema#label |
statin-induced myopathy
|
gptkbp:ICD-10_code |
G72.0
|
gptkbp:MeSH_ID |
D000071299
|
gptkbp:prevalence |
1-10% of statin users
|
gptkbp:riskFactor |
genetic predisposition
hypothyroidism older age renal impairment concomitant medications high statin dose |
gptkbp:symptom |
muscle pain
muscle weakness elevated creatine kinase muscle cramps |
gptkbp:treatment |
dose reduction
coenzyme Q10 supplementation statin discontinuation switching statin |
gptkbp:bfsParent |
gptkb:HMGCR
|
gptkbp:bfsLayer |
7
|