Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:medical_condition
gptkb:adverse_drug_reaction |
| gptkbp:canProgressTo |
rhabdomyolysis
|
| gptkbp:causedBy |
statins
|
| gptkbp:complication |
statin therapy
|
| gptkbp:diagnosedBy |
clinical evaluation
creatine kinase test |
| gptkbp:firstDescribed |
1990s
|
| gptkbp:ICD-10_code |
G72.0
|
| gptkbp:MeSH_ID |
D000071299
|
| gptkbp:prevalence |
1-10% of statin users
|
| gptkbp:riskFactor |
genetic predisposition
hypothyroidism older age renal impairment concomitant medications high statin dose |
| gptkbp:symptom |
muscle pain
muscle weakness elevated creatine kinase muscle cramps |
| gptkbp:treatment |
dose reduction
coenzyme Q10 supplementation statin discontinuation switching statin |
| gptkbp:bfsParent |
gptkb:HMGCR
gptkb:Coenzyme_Q10 gptkb:coenzyme_Q10 |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
statin-induced myopathy
|