Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:ATCCode |
gptkb:J01EE01
|
| gptkbp:contains |
trimethoprim
sulfamethoxazole |
| gptkbp:contraindication |
severe kidney disease
severe liver disease sulfonamide allergy |
| gptkbp:discoveredBy |
gptkb:Burroughs_Wellcome
|
| https://www.w3.org/2000/01/rdf-schema#label |
Co-trimoxazole
|
| gptkbp:introduced |
1970s
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits folic acid synthesis
|
| gptkbp:otherName |
gptkb:Bactrim
gptkb:trimethoprim/sulfamethoxazole Cotrim Septrin TMP-SMX |
| gptkbp:pregnancyCategory |
D (US)
|
| gptkbp:routeOfAdministration |
oral
intravenous |
| gptkbp:sideEffect |
nausea
vomiting rash bone marrow suppression hyperkalemia |
| gptkbp:usedFor |
gptkb:pneumocystis_pneumonia
gptkb:toxoplasmosis urinary tract infections shigellosis chronic bronchitis exacerbations |
| gptkbp:WHOModelListOfEssentialMedicines |
true
|
| gptkbp:bfsParent |
gptkb:trimethoprim-sulfamethoxazole
|
| gptkbp:bfsLayer |
6
|