Statements (57)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:pharmaceuticals
|
| gptkbp:administered_by |
suspension
oral tablet |
| gptkbp:approves |
gptkb:1973
gptkb:FDA |
| gptkbp:available_in |
liquid form
tablet form |
| gptkbp:available_on |
generic drug
|
| gptkbp:brand |
gptkb:Septra
Cotrim |
| gptkbp:can |
plenty of fluids
food to reduce stomach upset |
| gptkbp:can_cause |
gptkb:stevens-johnson_syndrome
liver damage kidney damage toxic epidermal necrolysis |
| gptkbp:contains |
gptkb:sulfamethoxazole
gptkb:trimethoprim |
| gptkbp:contraindication |
pregnancy
severe liver disease |
| gptkbp:developed_by |
gptkb:Glaxo_Smith_Kline
|
| gptkbp:dosage_form |
gptkb:tablet
suspension |
| https://www.w3.org/2000/01/rdf-schema#label |
Bactrim
|
| gptkbp:ingredients |
sinusitis
otitis media nocardiosis shigellosis |
| gptkbp:interacts_with |
gptkb:methotrexate
gptkb:phenytoin gptkb:warfarin |
| gptkbp:is_available_in |
various strengths
|
| gptkbp:is_effective_against |
fungal infections
viral infections parasitic infections |
| gptkbp:is_part_of |
combination therapy
antimicrobial therapy |
| gptkbp:is_used_in |
pediatric medicine
infectious disease treatment adult medicine |
| gptkbp:mechanism_of_action |
inhibits bacterial folic acid synthesis
|
| gptkbp:side_effect |
dizziness
fatigue headache nausea diarrhea rash |
| gptkbp:suitable_for |
infants under 2 months
patients with G6 PD deficiency patients with a history of hypersensitivity to sulfa drugs |
| gptkbp:treatment |
gptkb:pneumonia
bronchitis urinary tract infections traveler's diarrhea |
| gptkbp:used_for |
bacterial infections
|
| gptkbp:bfsParent |
gptkb:trimethoprim-sulfamethoxazole
|
| gptkbp:bfsLayer |
6
|