|
gptkbp:instanceOf
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:alsoKnownAs
|
gptkb:Secretin_receptor_family
|
|
gptkbp:discoveredBy
|
pharmacological classification
|
|
gptkbp:encodedBy
|
various genes
|
|
gptkbp:foundIn
|
invertebrates
vertebrates
|
|
gptkbp:function
|
activates G proteins
binds peptide hormones
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Class B (Secretin-like)
|
|
gptkbp:includes
|
gptkb:Calcitonin_receptor
gptkb:Glucagon_receptor
gptkb:Growth_hormone-releasing_hormone_receptor
gptkb:Parathyroid_hormone_receptor
gptkb:Secretin_receptor
gptkb:Vasoactive_intestinal_peptide_receptor
Corticotropin-releasing hormone receptor
|
|
gptkbp:InterPro
|
gptkb:IPR000832
|
|
gptkbp:involvedIn
|
regulation of metabolism
stress response
hormone signaling
calcium homeostasis
|
|
gptkbp:Membranome_Superfamily
|
201
|
|
gptkbp:OMIM
|
600001
|
|
gptkbp:partOf
|
gptkb:G_protein-coupled_receptors
|
|
gptkbp:proteinFamily
|
gptkb:PF00002
|
|
gptkbp:relatedTo
|
Class A (Rhodopsin-like) GPCRs
Class C (Metabotropic glutamate/pheromone) GPCRs
|
|
gptkbp:structure
|
7 transmembrane helices
contains large extracellular N-terminal domain
|
|
gptkbp:subfamily
|
B1 (Secretin receptor-like)
B2 (Adhesion GPCRs)
B3 (Methuselah-like GPCRs)
|
|
gptkbp:UniProt_Keyword
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:bfsParent
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:bfsLayer
|
5
|