Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
calcium/calmodulin
|
| gptkbp:alias |
CAMK2A protein
CAMKIIA CaMKII alpha |
| gptkbp:EC_number |
2.7.11.17
|
| gptkbp:expressedIn |
brain
hippocampus |
| gptkbp:fullName |
Calcium/calmodulin-dependent protein kinase type II alpha chain
|
| gptkbp:function |
serine/threonine-protein kinase
involved in synaptic plasticity regulates learning and memory |
| gptkbp:gene |
CAMK2A
|
| https://www.w3.org/2000/01/rdf-schema#label |
CaMKI alpha
|
| gptkbp:locatedOnChromosome |
5q32
|
| gptkbp:location |
gptkb:cytoplasm
postsynaptic density |
| gptkbp:molecularWeight |
54 kDa
|
| gptkbp:mutationAssociatedWith |
gptkb:autism_spectrum_disorder
intellectual disability |
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
2VZ6
|
| gptkbp:phosphorylates |
gptkb:CREB
AMPA receptor subunits |
| gptkbp:relatedTo |
CaMKII delta
CaMKII beta CaMKII gamma |
| gptkbp:structure |
holoenzyme forms dodecameric complex
|
| gptkbp:UniProtID |
Q9UQM7
|
| gptkbp:bfsParent |
gptkb:CaMKI
|
| gptkbp:bfsLayer |
8
|