|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:activatedBy
|
calcium/calmodulin
|
|
gptkbp:encodedBy
|
gptkb:CAMK1_gene
|
|
gptkbp:enzymeCommissionNumber
|
2.7.11.17
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
various tissues
|
|
gptkbp:foundIn
|
eukaryotes
|
|
gptkbp:fullName
|
gptkb:Calcium/calmodulin-dependent_protein_kinase_I
|
|
gptkbp:function
|
phosphorylates serine/threonine residues
|
|
gptkbp:gene
|
gptkb:CAMK1
|
|
gptkbp:hasIsoform
|
gptkb:CaMKI_alpha
gptkb:CaMKI_beta
gptkb:CaMKI_delta
gptkb:CaMKI_gamma
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CaMKI
|
|
gptkbp:involvedIn
|
gptkb:synaptic_plasticity
cell signaling
neuronal development
gene expression regulation
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
approximately 43 kDa
|
|
gptkbp:phosphorylates
|
gptkb:CREB
gptkb:synapsin_I
|
|
gptkbp:regulates
|
cell cycle progression
neurite outgrowth
autophosphorylation
dendritic development
phosphorylation by CaMKK
|
|
gptkbp:relatedTo
|
gptkb:CaMKIV
gptkb:CaMKII
|
|
gptkbp:structure
|
contains serine/threonine kinase domain
|
|
gptkbp:UniProtID
|
Q14012 (human)
|
|
gptkbp:bfsParent
|
gptkb:CKK
|
|
gptkbp:bfsLayer
|
7
|