Statements (17)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:affectsDrugMetabolism |
gptkb:phenytoin
gptkb:warfarin gptkb:NSAIDs |
gptkbp:affectsEnzymeActivity |
decreased
|
gptkbp:aminoAcidChange |
I359L
|
gptkbp:foundInPopulation |
global
|
gptkbp:frequencyInEastAsians |
~3%
|
gptkbp:frequencyInEuropeans |
~7%
|
gptkbp:hasNucleotideChange |
1075A>C
|
https://www.w3.org/2000/01/rdf-schema#label |
CYP2C9*3
|
gptkbp:locatedOnChromosome |
chromosome 10q23.33
|
gptkbp:rsID |
rs1057910
|
gptkbp:significance |
increased risk of adverse drug reactions
|
gptkbp:variant |
gptkb:CYP2C9
|
gptkbp:bfsParent |
gptkb:CYP2C9
|
gptkbp:bfsLayer |
5
|