Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:affectsDrugMetabolism |
gptkb:phenytoin
gptkb:warfarin gptkb:NSAIDs |
| gptkbp:affectsEnzymeActivity |
decreased
|
| gptkbp:aminoAcidChange |
I359L
|
| gptkbp:foundInPopulation |
global
|
| gptkbp:frequencyInEastAsians |
~3%
|
| gptkbp:frequencyInEuropeans |
~7%
|
| gptkbp:hasNucleotideChange |
1075A>C
|
| gptkbp:locatedOnChromosome |
chromosome 10q23.33
|
| gptkbp:rsID |
rs1057910
|
| gptkbp:significance |
increased risk of adverse drug reactions
|
| gptkbp:variant |
gptkb:CYP2C9
|
| gptkbp:bfsParent |
gptkb:CYP2C9
gptkb:P07014 |
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
CYP2C9*3
|