|
gptkbp:instanceOf
|
gptkb:protein
cytokine
|
|
gptkbp:alternativeName
|
C-X-C motif chemokine ligand 16
SR-PSOX
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cardiovascular_disease
autoimmune diseases
|
|
gptkbp:binds
|
oxidized low-density lipoprotein (oxLDL)
|
|
gptkbp:cleavage
|
gptkb:ADAM17
ADAM10
|
|
gptkbp:discoveredBy
|
Shimaoka et al.
|
|
gptkbp:discoveredIn
|
2000
|
|
gptkbp:encodes
|
C-X-C motif chemokine 16
|
|
gptkbp:Ensembl_ID
|
ENSG00000102970
|
|
gptkbp:Entrez_Gene_ID
|
58191
|
|
gptkbp:expressedIn
|
immune cells
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
chemotaxis
scavenger receptor activity
|
|
gptkbp:gene
|
gptkb:CXCL16
|
|
gptkbp:geneLocationEnd
|
7,053,222
|
|
gptkbp:geneLocationStart
|
7,048,964
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasMembraneBoundForm
|
true
|
|
gptkbp:HGNC_ID
|
HGNC:18141
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CXCL16
|
|
gptkbp:involvedIn
|
atherosclerosis
inflammatory response
immune cell migration
|
|
gptkbp:isSolubleIn
|
true
|
|
gptkbp:length
|
254 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:17p13.2
|
|
gptkbp:molecularWeight
|
28 kDa
|
|
gptkbp:OMIM
|
605794
|
|
gptkbp:orthologInMouse
|
Cxcl16
|
|
gptkbp:recipient
|
gptkb:CXCR6
|
|
gptkbp:regulates
|
inflammatory cytokines
macrophage recruitment
T cell migration
|
|
gptkbp:strand
|
plus
|
|
gptkbp:structure
|
contains transmembrane domain
contains cytoplasmic tail
contains chemokine domain
contains mucin-like stalk
|
|
gptkbp:transmembraneDomains
|
true
|
|
gptkbp:UniProtID
|
Q9H2A7
|
|
gptkbp:bfsParent
|
gptkb:CXC_domain
|
|
gptkbp:bfsLayer
|
8
|