|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
EMS1
FLJ90048
p80/85
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
cancer progression
|
|
gptkbp:discoveredBy
|
1992
|
|
gptkbp:encodes
|
cortactin protein
|
|
gptkbp:Entrez_Gene_ID
|
2017
ENSG00000143622
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:function
|
cell migration
endocytosis
regulation of actin cytoskeleton
|
|
gptkbp:HGNC_ID
|
2501
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CTTN gene
|
|
gptkbp:interactsWith
|
gptkb:Src_family_kinases
gptkb:dynamin
Arp2/3 complex
|
|
gptkbp:length
|
546 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:11q13
|
|
gptkbp:mutationAssociatedWith
|
may contribute to tumor metastasis
|
|
gptkbp:OMIM
|
604153
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Cttn
|
|
gptkbp:pathway
|
signal transduction
cell adhesion
actin polymerization
|
|
gptkbp:phosphorylates
|
tyrosine residues
|
|
gptkbp:product
|
gptkb:cortactin
|
|
gptkbp:proteinFamily
|
SH3 domain
proline-rich region
repeat domain
|
|
gptkbp:UniProtID
|
Q14247
|
|
gptkbp:bfsParent
|
gptkb:11q13
gptkb:cortactin
|
|
gptkbp:bfsLayer
|
8
|